TABLE 1.
Drug and penicillin susceptibilitya | MIC (μg/ml)
|
||
---|---|---|---|
Range | 50% | 90% | |
Penicillin | |||
S | 0.016-0.06 | 0.03 | 0.06 |
I | 0.125-1.0 | 0.25 | 1.0 |
R | 2.0-16.0 | 2.0 | 4.0 |
LBM415 | |||
S | 0.06-4.0 | 1.0 | 2.0 |
I | 0.03-2.0 | 0.5 | 1.0 |
R | 0.06-4.0 | 0.5 | 1.0 |
Amoxicillin | |||
S | ≤0.016-0.125 | 0.03 | 0.03 |
I | ≤0.016-2.0 | 0.25 | 1.0 |
R | 0.25-16.0 | 2.0 | 8.0 |
Amoxicillin-clavulanate | |||
Penicillin S | ≤0.016-0.125 | 0.03 | 0.03 |
Penicillin I | 0.03-2.0 | 0.25 | 1.0 |
Penicillin R | 0.25-16.0 | 2.0 | 4.0 |
Imipenem | |||
S | ≤0.004-0.03 | 0.008 | 0.008 |
I | 0.016-0.25 | 0.03 | 0.125 |
R | 0.06-2.0 | 0.25 | 0.25 |
Meropenem | |||
S | 0.008-0.06 | 0.016 | 0.016 |
I | 0.016-0.5 | 0.06 | 0.25 |
R | 0.125-2.0 | 0.5 | 0.5 |
Ceftriaxone | |||
S | 0.008-0.25 | 0.03 | 0.06 |
I | 0.03-1.0 | 0.125 | 1.0 |
R | 0.5->8.0 | 1.0 | 2.0 |
Cefuroxime | |||
S | 0.016-0.5 | 0.03 | 0.125 |
I | 0.125-4.0 | 0.25 | 4.0 |
R | 2.0-64.0 | 4.0 | 16.0 |
Ciprofloxacin | |||
S | 1.0->32.0 | 2.0 | 32.0 |
I | 0.5-32.0 | 1.0 | 2.0 |
R | 0.5->32.0 | 2.0 | 4.0 |
Levofloxacin | |||
S | 1.0-32.0 | 1.0 | 16.0 |
I | 0.5-32.0 | 1.0 | 2.0 |
R | 0.5-32.0 | 1.0 | 2.0 |
Gatifloxacin | |||
S | 0.25-8.0 | 0.5 | 4.0 |
I | 0.125-16.0 | 0.25 | 0.5 |
R | 0.125-16.0 | 0.5 | 1.0 |
Moxifloxacin | |||
S | 0.125-4.0 | 0.25 | 4.0 |
I | 0.06-4.0 | 0.125 | 0.25 |
R | 0.06-4.0 | 0.25 | 0.5 |
Azithromycin | |||
S | 0.03->64.0 | 2.0 | >64.0 |
I | ≤0.016->64.0 | 2.0 | >64.0 |
R | 0.06->64.0 | 0.125 | >64.0 |
Clarithromycin | |||
S | ≤0.016->64.0 | 0.5 | >64.0 |
I | ≤0.016->64.0 | 1.0 | >64.0 |
R | ≤0.016->64.0 | 0.06 | >64.0 |
Cefpodoxime | |||
S | 0.03-0.5 | 0.03 | 0.06 |
I | 0.06-4.0 | 0.25 | 2.0 |
R | 1.0-64.0 | 4.0 | 8.0 |
Cefdinir | |||
S | 0.016-0.5 | 0.06 | 0.125 |
I | 0.06-8.0 | 0.5 | 4.0 |
R | 2.0->64.0 | 8.0 | 8.0 |
S, susceptible (n = 80); I, intermediate (n = 88); R, resistant. (n = 132).