TABLE 1.

Agar dilution MICs for 300 strains classified by penicillin susceptibility

Drug and penicillin susceptibilitya	MIC (μg/ml)
	Range	50%	90%
Penicillin
S	0.016-0.06	0.03	0.06
I	0.125-1.0	0.25	1.0
R	2.0-16.0	2.0	4.0
LBM415
S	0.06-4.0	1.0	2.0
I	0.03-2.0	0.5	1.0
R	0.06-4.0	0.5	1.0
Amoxicillin
S	≤0.016-0.125	0.03	0.03
I	≤0.016-2.0	0.25	1.0
R	0.25-16.0	2.0	8.0
Amoxicillin-clavulanate
Penicillin S	≤0.016-0.125	0.03	0.03
Penicillin I	0.03-2.0	0.25	1.0
Penicillin R	0.25-16.0	2.0	4.0
Imipenem
S	≤0.004-0.03	0.008	0.008
I	0.016-0.25	0.03	0.125
R	0.06-2.0	0.25	0.25
Meropenem
S	0.008-0.06	0.016	0.016
I	0.016-0.5	0.06	0.25
R	0.125-2.0	0.5	0.5
Ceftriaxone
S	0.008-0.25	0.03	0.06
I	0.03-1.0	0.125	1.0
R	0.5->8.0	1.0	2.0
Cefuroxime
S	0.016-0.5	0.03	0.125
I	0.125-4.0	0.25	4.0
R	2.0-64.0	4.0	16.0
Ciprofloxacin
S	1.0->32.0	2.0	32.0
I	0.5-32.0	1.0	2.0
R	0.5->32.0	2.0	4.0
Levofloxacin
S	1.0-32.0	1.0	16.0
I	0.5-32.0	1.0	2.0
R	0.5-32.0	1.0	2.0
Gatifloxacin
S	0.25-8.0	0.5	4.0
I	0.125-16.0	0.25	0.5
R	0.125-16.0	0.5	1.0
Moxifloxacin
S	0.125-4.0	0.25	4.0
I	0.06-4.0	0.125	0.25
R	0.06-4.0	0.25	0.5
Azithromycin
S	0.03->64.0	2.0	>64.0
I	≤0.016->64.0	2.0	>64.0
R	0.06->64.0	0.125	>64.0
Clarithromycin
S	≤0.016->64.0	0.5	>64.0
I	≤0.016->64.0	1.0	>64.0
R	≤0.016->64.0	0.06	>64.0
Cefpodoxime
S	0.03-0.5	0.03	0.06
I	0.06-4.0	0.25	2.0
R	1.0-64.0	4.0	8.0
Cefdinir
S	0.016-0.5	0.06	0.125
I	0.06-8.0	0.5	4.0
R	2.0->64.0	8.0	8.0

^aS, susceptible (n = 80); I, intermediate (n = 88); R, resistant. (n = 132).