FIG. 1.
Tissue burden of kidneys of CD1 mice infected intravenously with 7.0 × 104 CFU of C. albicans # 2/mouse and treated with P (sterile saline solution) from day 1 to day 3 postinfection (P), CAS from day 1 to day 3 (CAS), or FLC from day 1 to day 3 (FLC) and sacrificed on day 4 postinfection or treated with P from day 1 to day 7 (P), CAS from day 1 to day 3 followed by P from day 4 to day 7 (CAS/P), P from day 1 to day 3 followed by FLC from day 4 to day 7 (P/FLC), CAS from day 1 to day 7 (CAS), FLC from day 1 to day 7 (FLC), or CAS from day 1 to day 3 followed by FLC from day 4 to day 7 (CAS/FLC) and sacrificed on day 8 postinfection. CAS and FLC were given at concentrations of 0.1 and 1 mg/kg of body weight/day, respectively (A), at 0.4 and 4 mg/kg/day, respectively (B), at 0.8 and 8 mg/kg/day, respectively (C), and at 0.4 and 8 mg/kg/day, respectively (D). The bars represent the medians. There were 10 mice in each group.