TABLE 2.
Demographic and clinical characteristics of patients with bloodstream infections due to AmpC β-lactamase-producing K. pneumoniae isolates versus those of patients with infections due to TEM- or SHV-related ESBL-producing K. pneumoniae isolates
Characteristic | AmpC group (n = 27) | ESBL group (n = 25) | P |
---|---|---|---|
Age (yr [mean ± SD]) | 54 ± 12.6 | 55 ± 17.7 | 0.872 |
No. (%) of male patients | 19 (70.4) | 14 (56) | 0.282 |
Underlying disease (no. [%] of patients) | |||
Leukemia | 1 (3.7) | 4 (16) | 0.183 |
Solid tumor | 7 (25.9) | 5 (20) | 0.612 |
Liver cirrhosis | 9 (33.3) | 4 (16) | 0.149 |
Pancreaticobiliary tract disease | 6 (22.2) | 0 (0) | 0.023 |
Others | 5 (18.5) | 12 (48) | |
Site of infection (no. [%] of patients) | |||
Cholangitis | 13 (48.1) | 7 (28) | 0.136 |
Peritonitis | 6 (22.2) | 4 (16) | 0.729 |
Liver abscess | 3 (11.1) | 1 (4) | 0.611 |
Pneumonia | 1 (3.7) | 3 (12) | 0.341 |
Urinary tract infection | 1 (3.7) | 2 (8) | 0.603 |
Unknown | 3 (11.1) | 8 (32) | 0.065 |
APACHE II score (mean ± SD) | 8.37 ± 4.44 | 10.68 ± 5.90 | 0.115 |