TABLE 3.
Analysis of risk factors for bloodstream infections caused by AmpC β-lactamase-producing K. pneumoniae isolates versus those caused by TEM- or SHV-related ESBL-producing K. pneumoniae isolates
| Risk factor | No. (%) of patients
|
P | |
|---|---|---|---|
| AmpC group (n = 27) | ESBL group (n = 25) | ||
| Long hospital stay (>2 wk) | 11 (40.7) | 16 (64) | 0.093 |
| Care in intensive care unit | 3 (11.1) | 5 (20) | 0.458 |
| Central venous catheterization | 8 (29.6) | 8 (32) | 0.853 |
| Indwelling urinary catheter | 7 (25.9) | 7 (28) | 0.866 |
| Polymicrobial infection | 9 (33.3) | 2 (8) | 0.025 |
| Invasive procedure within previous 72 h | 10 (37.0) | 4 (16) | 0.087 |
| Neutropenia | 2 (7.4) | 5 (20) | 0.241 |
| Postsurgical state | 4 (14.8) | 3 (12) | 1.000 |
| Nosocomial infection | 26 (96.3) | 21 (84) | 0.183 |
| Prior use of antibiotics | 21 (77.8) | 21 (84) | 0.729 |
| Broad-spectrum cephalosporins | 20 (74.1) | 18 (72) | 0.866 |
| Penicillins | 2 (7.4) | 6 (24) | 0.134 |
| Fluoroquinolones | 4 (14.8) | 2 (8) | 0.670 |
| Aminoglycosides | 15 (55.6) | 16 (64) | 0.535 |