TABLE 2.
Comparison of three models used to describe the interaction between enroxacin and E. colia
| Model | Equation | Parameters
|
Goodness of fit
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N0 (CFU/plate) | BC50 (μg/ml) | r | bottom (CFU/plate) | top (CFU/plate) | EC50 (μg/ml) | Hill slope | Emax (CFU/plate) | s | R2 | ASS | Sy.x | 95% CI of EC50/BC50 | % CVb of EC50/BC50 | ||
| CKC |  |
465 ± 6 | 0.440 ± 0.0036 | 20.34 ± 1.278 | 0.960 | 131,372 | 36.80 | 0.4328-0.4469 | 1.60 | ||||||
| Sigmoidal concn- response curve |  |
7 ± 8 | 482 ± 10 | 0.441 ± 0.0052 | 8.43 ± 0.758 | 0.949 | 247,030 | 46.15 | 0.4303-0.4510 | 2.34 | |||||
| Emax |  |
0.438 ± 0.0052 | 490 ± 11 | 8.25 ± 0.725 | 0.950 | 264,024 | 47.50 | 0.4279-0.4485 | 2.35 | ||||||
a
Data are from Fig. 4.
b
Relative CV = (high value of 95% CI − lower value of 95% CI)/(2× mean value).