TABLE 2.

In vitro activities of the combinations of compound 1 and-DDS, and chlorcyloguanil-DDS against P. falciparum V1S

Drug namea	Drug IC50 (nM) in presence of DDS	sFIC
Compound 1	0.08 (9,200)b	0.060
	0.09 (6,100)	0.043
	0.12 (4,600)	0.038
CCG	15.40 (9,200)	0.27
	17.90 (6,100)	0.29
	24.40 (4,600)	0.37

^aThe IC₅₀s of compound 1, CCG, and DDS alone were 9, 71, and 184, 300 nM, respectively.

^bValues in parentheses represent the concentrations of DDS (in nanomolar).