Table 1.
Characteristics | All | Genotype | Ribavirin | |||
---|---|---|---|---|---|---|
1a | 3b | Otherc | With | Without | ||
n = 249 | n = 187 | n = 40 | n = 22 | n = 66 | n = 183 | |
Age, median (years) | 56 | 56 | 55 | 55 | 55 | 57 |
Male (%) | 78 | 75 | 85 | 91 | 85 | 76 |
HIV co-infection (%) | 10 | 8 | 15 | 14 | 11 | 9 |
Prior HCV treatment (%) | 65 | 69 | 48 | 64 | 65 | 65 |
Cirrhosis (%) | ||||||
- No | 14 | 16 | 5 | 14 | 18 | 13 |
- Compensated | 27 | 21 | 48 | 36 | 27 | 26 |
- Decompensated | 59 | 63 | 48 | 50 | 55 | 61 |
Child Pugh class (%) | ||||||
- A | 27 | 27 | 20 | 41 | 29 | 26 |
- B | 33 | 37 | 23 | 14 | 33 | 32 |
- C | 8 | 9 | 3 | 9 | 5 | 9 |
- Unknown | 33 | 27 | 55 | 36 | 33 | 32 |
Fibrosis stage (%) | ||||||
- < F3 | 9 | 9 | 5 | 14 | 9 | 9 |
- F3 – F4 | 82 | 83 | 73 | 82 | 82 | 81 |
- Unknown | 10 | 8 | 23 | 5 | 9 | 10 |
Hepatocellular carcinoma (%) | ||||||
- Never | 58 | 56 | 65 | 68 | 61 | 57 |
- Past | 17 | 19 | 13 | 14 | 18 | 17 |
- Current | 12 | 13 | 10 | 9 | 15 | 12 |
- Unknown | 12 | 12 | 13 | 9 | 6 | 14 |
Liver transplantation (%) | ||||||
- Never | 34 | 31 | 50 | 32 | 27 | 36 |
- On list | 13 | 14 | 13 | 9 | 11 | 14 |
- Before current treatment | 40 | 40 | 33 | 50 | 44 | 38 |
- During current treatment | 11 | 13 | 3 | 9 | 12 | 10 |
- Unknown | 2 | 3 | 3 | 0 | 6 | 1 |
aGenotypes 1 (n = 14), 1a (n = 58), 1a/b (n = 3), and 1b (n = 112)
bGenotypes 3 (n = 18), 3a (n = 21) and 3 h (n = 1)
cGenotypes 2 (n = 4), 4 (n = 17) and 5 (n = 1)