Table 1.

Heart pathology scores based on evaluation of hematoxylin and eosin (HE) and trichome stained sections

Pathology		Interstitial cellularity					Vacuolization					Fibrosis					Cumulative
Degree		0	1	2	3	4	0	1	2	3	4	0	1	2	3	4	Mean	Median	95% CI
Male	Control	6	0	0	0	0	6	0	0	0	0	6	0	0	0	0	0	0	0
	DOX	0	2	2	0	0	0	1	2	1	0	1	3	0	0	0	4.25	4.5*	3–5
Female	Control	2	3	0	0	0	5	0	0	0	0	5	0	0	0	0	0.6	1	0–1
	DOX	0	4	1	0	0	3	2	0	0	0	3	2	0	0	0	2	2#	1–3

*p < 0.05 compared to saline-treated mice of the same sex; ^# p < 0.05 compared to male DOX-treated mice