Table 2.
q values for the effect of DOX, sex, and the interaction between sex and DOX in regulating CYP genes expression based on a 2-way ANOVA analysis and a 5% false discovery rate
| 1 day post-DOX | 6 days post-DOX | |||||
|---|---|---|---|---|---|---|
| DOX effect | Sex effect | Interaction effect | DOX effect | Sex effect | Interaction effect | |
| Cyp1a1 | 0.0001* | 0.3346 | 0.3865 | 0.4935 | 0.0064* | 0.1977 |
| Cyp1b1 | <0.0001* | <0.0001* | 0.0200* | 0.0013* | 0.0064* | 0.0831 |
| Cyp2c29 | 0.0012* | 0.0006* | 0.0200* | 0.86 | 0.0433* | 1.0000 |
| Cyp2c44 | 0.0013* | 0.051 | 0.1048 | 0.08 | 0.0064* | 0.9700 |
| Cyp2e1 | <0.0001* | 0.0164* | 0.0364* | 0.08 | 0.5371 | 1.0000 |
| Cyp2j9 | <0.0001* | 0.2994 | 0.0567 | 0.2812 | 0.0727 | 1.0000 |
| Cyp4a10 | <0.0001* | 0.0009* | 0.3627 | 0.0943 | 0.1776 | 1.0000 |
Specific post-hoc testing results can be found on the relevant figures
*q < 0.05 denotes discoveries