Table 2.

Results of disease-free survival analysis by Cox proportional hazards model for the ER+/HER2− tumors, n = 939

	Univariate				Multivariate
	HR	95%	CI	P value	HR	95%	CI	P value
Age (years)
35–50 vs < 35	0.386	0.196	0.763	0.006	0.342	0.170	0.687	0.003
51–65 vs < 35	0.477	0.238	0.959	0.038	0.454	0.220	0.936	0.032
> 65 vs < 35	0.378	0.140	1.021	0.055	0.274	0.080	0.938	0.039
pT
T2 vs T1	2.162	1.348	3.468	0.001	1.731	1.054	2.844	0.030
T3 vs T1	4.654	1.948	11.118	0.001	3.219	1.288	8.045	0.012
N
N1 vs N0	1.826	1.173	2.844	0.008	1.797	1.007	3.207	0.047
LVI
positive vs negative	1.831	1.099	3.048	0.020	1.332	0.776	2.284	0.298
Grade
III vs I/II	2.890	1.808	4.619	<0.001	1.785	1.059	3.010	0.030
Ki67(%)
10–30 vs ≤10	2.859	1.336	6.116	0.007	2.835	1.312	6.126	0.008
≥ 30 vs ≤10	5.394	2.732	10.651	<0.001	4.239	2.057	8.735	<0.001
PgR(%)
< 20 vs ≥20	1.273	0.778	2.083	0.336	0.799	0.472	1.355	0.405
Surgery
Mastectomy vs BCS	1.658	1.065	2.581	0.025	0.941	0.472	1.874	0.862
Chemotherapy
No vs Yes	0.731	0.376	1.419	0.354	1.430	0.620	3.298	0.402
Radiotherapy
No vs Yes	1.291	0.803	2.074	0.292	2.157	0.950	4.894	0.066