Table 3.
Association between expression of Cks1 and p27KIP1 and clinical pathological features of patients with NPC
| Characteristics | Cks1 | p27kip1 | ||||
|---|---|---|---|---|---|---|
| P (%) | N (%) | p-value | P (%) | N (%) | p-value | |
| Age (yr) | ||||||
| ≤ 50 (n = 101) | 73 (72.3) | 28 (27.7) | .859 | 15 (14.9) | 86 (85.1) | .382 |
| > 50 (n = 67) | 50 (74.6) | 17 (25.4) | 8 (11.9) | 59 (88.1) | ||
| Gender | ||||||
| Female (n = 41) | 32 (78) | 9 (22) | .421 | 4 (9.8) | 37 (90.2) | .399 |
| Male (n = 127) | 91 (71.7) | 36 (28.3) | 19 (15.0) | 108 (85.0) | ||
| Histological Type | ||||||
| DNC (n = 14) | 11 (78.6) | 3 (21.4) | .636 | 3 (21.4) | 11 (78.6) | .379 |
| UDNC (n = 154) | 112 (72.7) | 42 (27.3) | 20 (13.0) | 134 (87.0) | ||
| Clinical Stage | ||||||
| Stage I-II (n =45) | 30 (66.7) | 15 (33.3) | .246 | 5 (11.1) | 40 (88.9) | .556 |
| Stage III-IV (n =123) | 93 (75.6) | 30 (24.4) | 18 (14.6) | 113 (78.6) | ||
| LN Status | ||||||
| LNM (n = 125) | 111 (88.8) | 14 (11.2) | .007* | 16 (12.3) | 109 (87.2) | .567 |
| No LNM (n = 43) | 30 (69.8) | 13 (30.2) | 7 (16.3) | 36 (83.7) | ||
| Survival Status | ||||||
| Alive (n = 94) | 57 (60.6) | 37 (39.4) | .000* | 13 (13.8) | 81 (862) | .953 |
| Dead (n =74) | 66 (89.2) | 8 (10.8) | 23 (13.7) | 145 (86.3) | ||
Abbreviations: DNKC differentiated non-keratinized nasopharyngeal carcinoma, UDNC undifferentiated non-keratinized nasopharyngeal carcinoma, LN lymph node, LNM lymph node metastasis, P positive, N negative
Note: chi-square test, *: p < 0.05