Table 3.

Outcome of NIV and standard oxygen therapy for included studies

Study/year	ICU mortality (%)		Hospital mortality (%)		28-day mortality (%)		Long-term mortality (%)		Mortality in patients with ET (%)		Intubation rate (%)		Length of ICU stay (days)
	NIV	Ctrl	NIV	Ctrl	NIV	Ctrl	NIV	Ctrl	NIV	Ctrl	NIV	Ctrl	NIV	Ctrl
Antonelli et al. 2000 [10]	20	50	35	55	NR	NR	NR	NR	100	71.4	20	70	7 ± 5	10 ± 6
Hilbert et al. 2001 [11]	38.5	69.2	50	80.8	NR	NR	NR	NR	100	100	46.2	76.9	7 ± 3	9 ± 4
Squadrone et al. 2010 [12]	NR	NR	15	75	NR	NR	NR	NR	100	100	10	70	0 (0–28)	28 (0–28)
Wermke et al. 2012 [13]	NR	NR	NR	NR	NR	NR	39	32	100	100	14.3	25	NR	NR
Lemiale et al. 2015 [14]	20.9	24.6	30.9	34.4	24.1	27.3.	39.6	45.3	NR	NR	38.2	44.8	7 (3–16)	6 (3–16)

Ctrl control, ET endotracheal intubation, ICU intensive care unit, NIV noninvasive ventilation, NR not reported