Table 1. Analysis of the IgG1–4 subclass reactivity and IgA and IgM responsiveness to Bet v 1.
| Placebo
|
Fragments
|
Trimer
|
||||
|---|---|---|---|---|---|---|
| Ab class/subclass | Before | After | Before | After | Before | After |
| IgG1 | 0.159 | 0.152 | 0.152 | 0.566 | 0.188 | 0.836 |
| IgG2 | 0.046 | 0.044 | 0.054 | 0.265 | 0.058 | 0.319 |
| IgG3 | <0.040 | <0.040 | <0.040 | <0.040 | <0.040 | <0.040 |
| IgG4 | 0.042 | 0.039 | 0.031 | 0.269 | 0.033 | 0.476 |
| IgA | 0.224 | 0.222 | 0.262 | 0.345 | 0.314 | 0.435 |
| IgM | 0.219 | 0.211 | 0.151 | 0.142 | 0.216 | 0.301 |
Mean OD values corresponding to the amount of Bet v 1-specific Abs are given for the three groups (placebo, n = 27; fragments, n = 18; and trimer, n = 21) before and after treatment.