Table 2. Cross-reactivity of therapy-induced IgG1 Abs with major allergens.
| Alder
|
Hazel
|
Celery
|
Carrot
|
Apple
|
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Group | Before | After | Before | After | Before | After | Before | After | Before | After |
| Placebo | 0.125 | 0.121 | 0.086 | 0.082 | 0.048 | 0.043 | 0.087 | 0.084 | 0.087 | 0.081 |
| Active treatment | 0.067 | 0.439 | 0.056 | 0.312 | 0.048 | 0.140 | 0.066 | 0.127 | 0.050 | 0.191 |
Major allergens are as follows: alder pollen, Aln g 1; hazel pollen, Cor a l; celery, Api g 1; carrot, Dau c 1; and apple, Mal d 1. Results are given for patients showing improvement of their birch-pollen allergy-associated oral allergy syndrome (n = 7) vs. a randomly selected placebo group (n = 7). Mean OD values corresponding to the amount of allergen-specific Abs are given for the three groups before and after treatment.