Table 3. Cells, factors, and functions in adaptive immunity.
| Cells and systems | Important functions |
|---|---|
| APCs | Detect, engulf antigens, present fragments |
| Dendritic cells | Prime lymphocytes, secrete cytokines |
| Macrophages | Phagocytose, present, secrete cytokines |
| B cells | Engulf antigens, process, present fragments, differentiate, produce antibody |
| T cells | |
| CD8+ cytotoxic killer | Recognize, kill, secrete cytokines |
| Natural killer T cells | Recognize lipid antigens |
| CD4+ Helper* | |
| T helper 1 | Secrete cytokines, aid humoral responses |
| T helper 2 | Secrete cytokines, aid cytotoxic T cells |
| Suppressor T cells | Suppress T or B cell responses |
T helper 1 and 2 cytokines are mutually antagonistic.