Table 5. Examples of interruption of cytokines by virus-encoded proteins.

Interrupt cytokine production

Interfere with cytokine and chemokine synthesis

Halt maturation of cytokines

Interfere with cytokine signaling

Encode homologs of cellular cytokine and chemokine receptors

Viral encoded receptors give false signals, and interfere with chemokine trafficking

Viral molecules neutralize cytokines and inactivate cell receptors

Interfere with cytokine effector function

Inhibit or alter cytokine transduction pathways

Degrade messenger RNA, inhibit protein synthesis

Tolarella et al. (11) was the source for this information.