Figure 1.
A) PAS and Alcian Blue staining of murine BE metaplasia in the cardia showing mucus producing cells; B) Correlation of mucus cell ratio (%) with the tumor score; (%) of area containing mucus producing cells was counted in the metaplastic and dysplastic area of the mouse forestomach (ANOVA p<0.0001, R square 0.6951, F 39.52) C) PAS and Alcian Blue staining of human BE metaplasia showing specialized intestinal metaplasia with GCs; D) Boxplot of the GC ratio in human biopsies from BE or adjacent to EAC tissue with bars marking mean values (0.69 vs. 0.41 in BE and EAC resp., p<0.0001) and whiskers defining range from Min to Max.