Table 7.

Genome-wide studies with large samples, replication samples, or both

Measure	Lead Author (Year)	N (replication N)	Largest Effect
GWAS
MMN	Roeske (2011)	200 (184)	10.53%
Resting EEG theta power	Hodgkinson (2010)	322 (185)	8.8% (3.5%)
P50	Hall (2015)	392	9.05%
PPI	Roussos (2015)	792 (405)	?
Event-related theta power	Zlojutro (2011)	1,064 (1,095)	2.26% (0.42%)
Event-related theta power	Kang (2012)	1,560	0.91%
Resting heart rate	Deo (2013)	13,372	0.42%
Resting heart rate	Holm (2010)	23,112	0.28%
Resting heart rate	Cho (2009)	17,899	0.22%
Resting heart rate	Eijgelsheim (2010)	38,991	0.17%
Exome chip
N4S response to pre-pulse	Norden-Krichmar (2015)	420	1.97%

Note: The column labeled “N (Replication N)” lists the number of subjects in each study, or in the Stage 1 sample if the study included a replication study. The number of subjects in the replication sample is provided in parentheses if applicable. The effect size of the largest association is provided in the last column, as a percentage of endophenotype variance accounted for. For studies including a replication sample (and analyzing discovery and replication samples separately), the variance accounted for in the replication by the variant is provided in parentheses. To avoid redundancy, we did not include GWAS results from the 17 endophenotypes examined in our special issue of Psychophysiology, which are summarized in Table 2, despite representing a different set of endophenotypes. In addition, we did not include results we obtained for event-related theta power described in section 5.2, although this measure that appears in this table.