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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Transplantation. 2017 Jun;101(6):1479–1487. doi: 10.1097/TP.0000000000001314

Figure 1. Increased frequency of IFN-γ secreting T cells in BK virus controllers versus noncontrollers after viremia start.

Figure 1

PBMCs were incubated with overlapping peptide pools representing all 5 BK virus expressed proteins and analyzed by intracellular cytokine analysis. Panel A shows frequency of BK virus-specific CD8+ T cells expressing single cytokines IFN-γ, TNF-α, and IL-2. Panel B shows frequency of BK virus-specific CD4+ T cells expressing single cytokines IFN-γ, TNF-α, and IL-2. Double asterisk indicates p<0.01, single asterisk indicates p<0.05. Controllers are indicated by triangles, noncontrollers by circles, and patients with low level viremia by grey squares.