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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Transplantation. 2017 Jun;101(6):1479–1487. doi: 10.1097/TP.0000000000001314

Figure 4. Increased frequency of polyfunctional T cells in BK virus controllers versus noncontrollers over time.

Figure 4

PBMCs were incubated with overlapping peptide pools representing all 5 BK virus expressed proteins and analyzed by intracellular cytokine analysis. Differences in frequency of CD4+ and CD8+ T cells were seen over time in the controller versus noncontroller or low level viremia groups. Box and whiskers plot drawn using the Tukey method. Panel A, total polyfunctional CD8+ T cells. Panel B, total polyfunctional CD8+ T cells. Single asterisk indicates p<0.05 by Wilcoxon test. Controllers are indicated in black, and noncontrollers in grey.