Figure 1. John Cunningham polyomavirus (JCPyV) load values found in cancerous and benign bladder tissue and in urine specimens of patients with bladder carcinoma (BC). A statistically significant difference was obtained comparing the JCV loads detected (A) in patients with neoplastic and benign bladder tissues (p=0.046) and (B) in urine specimens of patients with high- (HGBC) and low-grade (LGBC) urothelial carcinoma and bladder hyperplasia (p=0.049). NB: Normal bladder; HG-U: urine from patients with HGBC; LG-U: urine from patients with LGBC; BH-U: urine from patients with bladder hyperplasia.