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. 2016 Sep 14;9(1):22–32. doi: 10.1159/000448808

Fig. 5.

Fig. 5

Cl-amidine treatment improves survival in the CLP sepsis model. Mice were divided into randomized groups and treated with a 50 mg/kg dose of Cl-amidine or 1× PBS (vehicle control) by subcutaneous injection 30–60 min prior to CLP and then once a day for 7 days after the procedure. The Cl-amidine-treated group had a 100% survival rate compared to the control group, which had a 45% survival rate. Sham animals had a 100% survival rate (data not shown). Sham, n = 3; CLP, n = 12 per group. * p < 0.05, log-rank test.