Table 1. Comparison of the principal components (PCs) of the two controls group extracted from T1ρ maps and normalized Z-score maps. Averages and standard deviation are presented normalized between 0 and 1 to allow direct comparison between the 2 models.
| Principal components | T1ρ PCA (mean, SD) | Z-score PCA (mean, SD) | |||||
|---|---|---|---|---|---|---|---|
| Control group 1 (N=25) | Control group 2 (N=10) | P value | Control group 1 (N=25) | Control group 2 (N=10) | P value | ||
| PC1 | (1.00, 0.06) | (0.97, 0.09) | 0.2561 | (1.00, 0.18) | (1.00, 0.28) | 0.9927 | |
| PC2 | (0.35, 0.03) | (0.39, 0.12) | 0.0826# | (0.49, 0.11) | (0.49, 0.19) | 0.9865 | |
| PC3 | (0.33, 0.03) | (0.32, 0.07) | 0.0643# | (0.38, 0.11) | (0.44, 0.08) | 0.9582 | |
| PC4 | (0.43, 0.04) | (0.38, 0.04) | 0.2275 | (0.70, 0.13) | (0.68, 0.10) | 0.9839 | |
| PC5 | (0.32, 0.03) | (0.29, 0.04) | 0.0002* | (0.39, 0.12) | (0.44, 0.10) | 0.9755 | |
| PC6 | (0.22, 0.04) | (0.22, 0.02) | 0.0448* | (0.37, 0.09) | (0.49, 0.09) | 0.9987 | |
| PC7 | (0.27, 0.03) | (0.26, 0.03) | 0.0038* | (0.53, 0.10) | (0.48, 0.09) | 0.9735 | |
| PC8 | (0.11, 0.02) | (0.11, 0.04) | 0.0054* | (0.47, 0.12) | (0.44, 0.07) | 0.9960 | |
| PC9 | (0.13, 0.03) | (0.06, 0.05) | 0.0008* | (0.36, 0.09) | (0.34, 0.07) | 0.9961 | |
| PC10 | (0.15, 0.03) | (0.14, 0.06) | 0.6686 | (0.40, 0.09) | (0.33, 0.05) | 0.9966 | |
*, independent t-test significant P vale<0.05; #, approaching significant P value <0.1. PCA, principal component analysis; SD, standard deviations.