Fig. 2.

TPH induced GES-1 cell proliferation.

TPH transfected the GES-1 cells. After incubation at 37°C for 48 hours, cell proliferation was measured by an MTT assay. TPH group: 3 × 10³ cells/well (transfected by TPH strain) in a 96-well plate incubated at 37°C for 48 hours; TP group: 3 × 10³ cells/well (transfected by TP strain) in a 96-well plate incubated at 37°C for 48 hours; control group: 3 × 10³ cells/well (transfected by PBS) in a 96-well plate incubated at 37°C for 48 hours.

GES-1 = gastric epithelial cells, MTT = 2-(4,5-dimethyltriazol-2-yl)-2,5-diphenyl tetrazolium bromide, TPH = attenuated Salmonella typhimurium strain carrying a eukaryotic expression vector encodes the human HGF gene, TP = attenuated Salmonella typhimurium strain with a eukaryotic expression vector, PBS = phosphate buffer solution.

^*P < 0.01, TPH group vs. TP and control groups.