Fig. 6.

Quantification of MVD on day 21 in granulation tissue from the ulcer beds by immunoreaction with CD34.

Data are presented as mean ± standard error (n = 50). The MVD in the TPH-treated group increased compared to the TP (a recombinant attenuated Salmonella strain carrying a eukaryotic expression vector)-treated and model control groups, with a significant statistical difference. The MVD in the TP-treated group was not significantly different compared with the model control group.

MVD = microvascular density, TPH = attenuated Salmonella typhimurium strain carrying a eukaryotic expression vector encodes the human HGF gene, TP = attenuated Salmonella typhimurium strain with a eukaryotic expression vector.

^*P < 0.01, TPH group vs. TP and control groups.