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. 2016 Dec 1;32(2):195–203. doi: 10.3346/jkms.2017.32.2.195

Table 2. Chemotherapy regimens.

Regimens Drugs Doses, mg/m2/day Schedules Total doses, mg/m2
Induction regimens
 CECV* Cisplatin 90 Day 0 90
Etoposide 75 Days 0–2 225
Cyclophosphamide 1,500 Days 1 and 2 3,000
Vincristine 1.5 Days 0 and 7 3
 VICE* Carboplatin 300 Days 0 and 1 600
Etoposide 75 Days 0–4 375
Ifosfamide 1,500 Days 0–4 7,500
Vincristine 1.5 Days 0 and 7 3
First HDCT regimen
 CTE Carboplatin 500 Days –8, –7, –6 1,500
Thiotepa 300 Days –5, –4, –3 900
Etoposide 250 Days –5, –4, –3 750
Second HDCT regimen
 CyM Cyclophosphamide 1,500 Days –8, –7, –6, –5 6,000
Melphalan 60 Days –4, –3, –2 180

CECV = cisplatin + etoposide + cyclophosphamide + vincristine, VICE = vincristine + ifosfamide + carboplatin + etoposide, CTE = carboplatin + thiotepa + etoposide, CyM = cyclophosphamide + melphalan, HDCT = high-dose chemotherapy.

*Dose was determined based on body weight in children under 3 years of age.