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. 2016 Dec 12;32(2):343–351. doi: 10.3346/jkms.2017.32.2.343

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© 2017 The Korean Academy of Medical Sciences.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 2 — Nestin and CD11bexpression in control and degenerated adult mouse retina.

Immunofluorescent labeling with nestin (green), CD11b (red), and DAPI (blue) is shown. Arrows indicate nestin/CD11b co-immunolabeling. After a single injection of MNU, nestin+/CD11b+ cells migrated into the ONL at day 3 and showed a peak at day 5. The number of nestin+/CD11b+ cells diminished progressively, particularly after 7 days, with sparse distribution by day 21.

DAPI = 4-6-diamino-2-phenylindole, ONL = outer nuclear layer, MNU = N-methyl-N-nitrosourea, OPL = outer plexiform layer, INL = inner nuclear layer, IPL = inner plexiform layer.