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The average number of Fos-positive cell nuclei per section in the arcuate (ARC), paraventricular (PVN) and supraoptic (SON) nuclei after intracerebroventricular injection saline (control) (n = 5) (5 μl), leptin (n = 5) (7 μg/5 μl), insulin (n = 4) (500 mU/5 μl), and the combination of leptin and insulin (n = 4). *P < 0.01 compared to saline; #P < 0.05 compared to insulin alone.
