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Resting mean arterial pressure (MAP) and heart rate (HR) prior to intracerebroventricular injection of saline (n = 5), leptin (7 μg, n = 5), insulin (500 mU, n = 4) and the combination of leptin and insulin (n = 4) in anesthetised rats.
| Saline | Leptin | Insulin | Leptin + Insulin | |
|---|---|---|---|---|
| MAP (mmHg) | 93.5 ± 4.1 | 79.7 ± 1.6 | 88.0 ± 6.8 | 86.2 ± 5.6 |
| HR (beats/min) | 360 ± 7 | 336 ± 11 | 312 ± 19 | 318 ± 28 |
