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. 2004 Oct 4;101(41):14853–14858. doi: 10.1073/pnas.0405338101

Table 1. Distribution of mature CD4 and CD8 T cells in spleen and lymph nodes of mutant mice.

Genotype Total cells (× 106) % CD4 % CD8 CD4/CD8 % CD4 CD25+ %CD8 CD25+
Spleen
    LMC, 4-5 wk 65 ± 13 16.0 ± 5.2 7.0 ± 3.5 2.3 12.4 ± 3.0 2.6 ± 2.0
    F/F/LckCre, 4-5 wk (n = 7) 68 ± 31 9.7 ± 3.7* 5.1 ± 2.3 1.9 21.5 ± 2.0* 8.4 ± 3.3*
    LMC, 4-9 wk 102 ± 41 19.9 ± 2.2 11.3 ± 1.4 1.8 11.3 ± 1.4 7.7 ± 6.0
    F/F/CD4Cre, 4-9 wk 74 ± 32 11.8 ± 1.7* 9.1 ± 1.6* 1.3 13.6 ± 2.9 10.0 ± 6.7
Lymph node
    LMC, 4-5 wk 43 ± 3 30 ± 4 1.4 13.6 ± 2.1 2.4 ± 2
    F/F/LckCre, 4-5 wk (n = 3) 23 ± 3* 23 ± 4 1.0 29.1 ± 2.0* 8.6 ± 3*
    LMC, 4-9 wk 37 ± 4 24 ± 3 1.5 13.1 ± 2.1 1.7 ± 1.2
    F/F/CD4Cre, 4-9 wk 28 ± 2* 24 ± 4 1.2 17.7 ± 2.0* 3.0 ± 1.9*

Percentages of CD4 CD25+ and CD8 CD25+ represent the total CD4 and CD8 T cells, respectively. *, P < 0.05.