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Diaphragm Nox2 mRNA and protein levels are increased in patients with end-stage HF. mRNA levels (A,C) and protein (B,D) of Nox2 subunits. Controls (open boxes; n = 3) and HF patients (gray boxes; n = 9–11). (C,D) are individual data from patients normalized to average of controls (dotted line), as in (A,B). (E) Representative immunoblots and protein gel. *P < 0.05 by Mann-Whitney test.
