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. 2016 Oct 26;117(1):251–259. doi: 10.1152/jn.00703.2016

Fig. 2.

Fig. 2.

Responses of DRG cells to 5-HT are enhanced by innocuous warming (35°C). A: representative examples of two DRG cells' responses to 5-HT (100 μM, 30 sec), followed by high potassium solution (HiK) at the indicated bath temperatures. Response was considerably larger at 35°C. B: representative examples of two DRG cells' responses to histamine (100 μM, 30 sec) at the indicated bath temperatures. Responses at both temperatures were of similar magnitude. C: mean responses of DRG cells to 5-HT (black square) or histamine (gray circle) at each tested temperature. Each data point is a separate group of DRG cells (see Table 1). Peak responses to 5-HT were significantly enhanced at 35°C relative to those at other lower temperatures (*P < 0.05, one-way ANOVA). In contrast, mean peak responses to histamine did not significantly differ across temperatures.