Table 2. Responses by prior lines of therapy.

	1 Prior line		⩾2 Prior lines
	Kd (n=232)	Vd (n=232)	Kd (n=232)	Vd (n=233)
Best overall response, n (%)
Stringent complete response	6 (2.6)	6 (2.6)	2 (0.9)	3 (1.3)
Complete response	21 (9.1)	12 (5.2)	29 (12.5)	8 (3.4)
Very good partial response	117 (50.4)	53 (22.8)	77 (33.2)	51 (21.9)
Partial response	46 (19.8)	80 (34.5)	58 (25.0)	77 (33.0)
Overall response rate, % (95% CI)	81.9 (76.3–86.6)	65.5 (59.0–71.6)	72.0 (65.7–77.7)	59.7 (53.1–66.0)
Median duration of response, months (95% CI)	21.3 (17.6–NE)	14.1 (8.6–NE)	NE (13.9–NE)	10.3 (9.0–12.2)

Abbreviations: CI, confidence interval; Kd, carfilzomib and dexamethasone; NE, not estimable; Vd, bortezomib and dexamethasone.