Table 1. Univariable Cox regression of miRNAs and ccRCC recurrence in the discovery and validation phases.

		Discovery			Validation
miRNA	Up/down in patients with recurrence	HR	95% CI	P-value	HR	95% CI	P-value	Obesity related
miR-204-5pa	Down	0.55	0.35–0.86	0.009	0.85	0.77–0.94	0.001	Yes
High expressionb		Ref.
Low expressionb		3.15	1.47–6.76	0.003	3.01	1.34–6.80	0.008
miR-139–5pa	Down	0.39	0.23–0.68	<0.001	0.74	0.62–0.88	<0.001	No
High expressionb		Ref.
Low expressionb		3.10	1.45–6.62	0.003	2.79	1.29–6.03	0.009

^aUnivariable Cox regression with miRNAs (−ΔΔCt) modelled as continuous variables.

^bLevels were dichotomised according to median level in non-recurrence patients.