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Up-regulating MBD3 inhibits the ability of invasion in pancreatic cancer cells. (A) The invasion ability was examined using BD Matrigel invasion assay in PaTu8988 and SW1990 cells transfected with Vector or Flag-MBD3 plasmids. Magnification, × 20; bars, 50 μm. (B) Invasive cells were counted and analysed. **P<0.01, ***P<0.001. MMP2 and MMP9 were determined using western blotting (C) and real-time PCR (D) in above cells. *P<0.05, **P<0.01.
