Table 5. Correlations between inflammatory cytokines and measures of adiposity and muscle characteristics (with and without controlling for age) according to adiposity (normal vs high).
Variable |
Cytokine |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Normal adiposity (n=39) |
High adiposity (n=39) |
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IL-6 | IL-1β | IL-1β (age) | IL-8 (age) | TNF-α | MIP-1β | MIP-1β (age) | IL-6 | IL-8 | IL-8 (age) | MCP-1 (age) | G-CSF | G-CSF (age) | MIP-1β (age) | |
BMI (kgm-2) | r=0.386; P=0.015 | |||||||||||||
BF% | r=−0.391; P=0.014 | |||||||||||||
FM (kg) | r=−0.417; P=0.008 | r=0.332; P=0.039 | r=0.507; P=0.010 | |||||||||||
iMVC (N·m) | r=0.363; P=0.025 | r=−0.396; P=0.014 | ||||||||||||
ikMVC (N·m) | r=0.457; P=0.004 | r=0.793; P=0.022 | ||||||||||||
Ft (N) | r=0.393; P=0.015 | r=−0.412; P=0.010 | r=−0.364; P=0.044 | |||||||||||
GM Ff (N) | r=0.387; P=0.016 | r=−0.401; P=0.013 | ||||||||||||
Sp. force (Ncm-2) | r=−0.432; P=0.015 | r=0.594; P=0.009 | r=0.848; P=0.033 | |||||||||||
iMVC/Vm (N·mcm-3) | r=0.517; P=0.040 | r=−0.456; P=0.010 | r=0.901; P=0.014 | |||||||||||
ikMVC/Vm (N·mcm-3) | r=0.643; P=0.024 | r=0.604; P=0.038 | ||||||||||||
iMVC/BM (N·mkg-1) | r=−0.378; P=0.028 | |||||||||||||
ikMVC/BM (N·mkg-1) | r= − 0.367; P=0.042 | |||||||||||||
GM Vm (cm3) | r=0.695; P<0.001 | r=0.868; P<0.001 | ||||||||||||
GM PCSA (cm2) | r=0.550; P=0.001 | r=0.739; P=0.006 |
Abbreviations: BF, body fat; BM, body mass; BMI, body mass index; FM, fat mass; Ft, maximum Achilles tendon force; G-CSF, granulocyte-colony stimulating factor; GM Ff, maximum gastrocnemius medialis muscle fascicle force; GM Vm, gastrocnemius medialis muscle volume; ikMVC, isokinetic maximum voluntary contraction; IL, interleukin; iMVC, isometric maximum voluntary contraction; Lf, fascicle length; LM, lean mass; PCSA, physiological cross-sectional area; Sp. force, gastrocnemius muscle specific force; VA, voluntary muscle activation; θp, fascicle pennation angle.
Inverse correlations are indicated in bold.