Table 1.

Animal groups and respective treatments

Groups		Treatments
1	Control (C)	Solvents (DMSO 80 µl+PBS1)
2	LPS (L)	2 mg/kg
3	Compound-C (CC)	20 mg/kg
4	Metformin (M)	100 mg/kg
5	A-769662 (A)	10 mg/kg
6	Metformin+compound-C (M+CC)	100 mg/kg+20 mg/kg
7	A-769662+compound-C (A+CC)	10 mg/kg+20 mg/kg
8	Metformin+LPS (M+L)	100 mg/kg+2 mg/kg
9	A-769662+LPS (A+L)	10 mg/kg+2 mg/kg
10	Metformin+LPS+compound-C (M+L+CC)	100 mg/kg+2 mg/kg+20 mg/kg
11	A-769662+LPS+compound-C (A+L+CC)	10 mg/kg+2 mg/kg+20 mg/kg

¹phosphate buffer solution