Table 4.
Antimicrobial activity of methanol extracts of Mindium. laevigatum
Microbial strain | Plant extract | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rahagh area | Shahsavaran valley | Antibiotic | ||||||||||||
Fruit | Stem | Fruit | Stem | Rifampin | Gentamicin | Nystatin | ||||||||
DDa | MICb | DD | MIC | DD | MIC | DD | MIC | DD | MIC | DD | MIC | DD | MIC | |
Gram-positive bacteria | ||||||||||||||
B. subtilis | 13 | >500 | - | NTc | - | NT | - | NT | 13 | 15.62 | 21 | 500 | NA | NA |
S. epidermidis | 24 | >500 | 12 | >500 | 13 | >500 | 22 | >500 | 40 | 250 | 35 | 500 | NA | NA |
S. aureus | - | NT | - | NT | - | NT | - | NT | 10 | 250 | 21 | 500 | NA | NA |
Gram-negative bacteria | ||||||||||||||
E. coli | - | NT | - | NT | - | NT | - | NT | 11 | 500 | 20 | 500 | NA | NA |
k. pneumonia | 10 | >500 | - | NT | 8 | >500 | 18 | >500 | 7 | 250 | 22 | 250 | NA | NA |
S. dysenteriae | 10 | >500 | - | NT | 11 | >500 | - | NT | 8 | 250 | 18 | 500 | NA | NA |
P. vulgaris | 12 | >500 | - | NT | 10 | >500 | - | NT | 10 | 125 | 23 | 500 | NA | NA |
S. paratyphi-A serotype | - | NT | - | NT | - | NT | - | NT | - | NT | 21 | 500 | NA | NA |
Fungi | ||||||||||||||
C. albicans | - | NT | - | NT | - | NT | - | NT | NA | NA | NA | NA | 33 | NT |
A. niger | - | NT | - | NT | - | NT | - | NT | NA | NA | NA | NA | 27 | NT |
A. brasilienis | - | NT | - | NT | - | NT | - | NT | NA | NA | NA | NA | 23 | NT |
A dash (-) indicate no antimicrobial activity. aInhibition zone in diameter (mm) around the impregnated discs; bMinimal Inhibition concentrations (as μg/ml); c Samples with no activity in disc diffusion test and nystatin were not entered into the MIC test. NT (Not tested); NA (Not applicable)