Table 4.
Pathway analyses from genetic associations with perianal CD from Ichip analyses
Number of Genes |
p-value | p-value (FDR) |
p-value (Bonferroni) |
|
---|---|---|---|---|
JAK-STAT signaling pathway |
9 | 1.76 × 10−07 | 3.72 × 10−05 | 3.72 × 10−05 |
Leishmaniasis | 5 | 0.001 | 0.13 | 0.27 |
Phagosome | 6 | 0.003 | 0.18 | 0.64 |
Antigen processing and presentation |
5 | 0.004 | 0.18 | 0.84 |
ABC transporters | 3 | 0.004 | 0.18 | 0.89 |
CD, Crohn’s disease; JAK-STAT, Janus Kinase-Signal Transducer and Activator of Transcription; ABC, ATP-binding cassette transporters; FDR, false discover rate