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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Inflamm Bowel Dis. 2016 Apr;22(4):862–869. doi: 10.1097/MIB.0000000000000705

Table 4.

Pathway analyses from genetic associations with perianal CD from Ichip analyses

Number
of Genes
p-value p-value
(FDR)
p-value
(Bonferroni)
JAK-STAT signaling
pathway
9 1.76 × 10−07 3.72 × 10−05 3.72 × 10−05
Leishmaniasis 5 0.001 0.13 0.27
Phagosome 6 0.003 0.18 0.64
Antigen processing and
presentation
5 0.004 0.18 0.84
ABC transporters 3 0.004 0.18 0.89

CD, Crohn’s disease; JAK-STAT, Janus Kinase-Signal Transducer and Activator of Transcription; ABC, ATP-binding cassette transporters; FDR, false discover rate