Table 1.

Results of competitive binding assays in which fluorescein-labeled RBP was mixed with Rev protein, then competed with increasing amounts of the compounds indicated. See Supp. Fig. S3 for the primary data. The cyclic compounds have an amide bond between the N-terminal amine and the C-terminal carboxylate.

Name	Sequence	IC50 [nM]
RBP	YPAASYR	179 ± 15
CyAla2	YcAAASYR	209 ± 17
CyAla3	YPcAASYR	218 ± 15
CyAla4	YPAcASYR	257 ± 17
CyAla5	YPAAcAYR	293 ± 9
CyAla6	YPAAScAR	>650
CyAla7	YPAASYcA	323 ± 20
CyAla3,4	YPcAcASYR	205 ± 15
cRBP	cyclo-YPAASYR	28 ± 5
cCyAla3,4	cyclo-YPcAcASYR	28 ± 2
scr cCyAla3,4	cyclo-YScAYcARP	>5000
FLAG	DYKDDDDK	>5000