Table 3. Hazard ratios (95% CI) of all-cause mortality stratified analysis by sex.
Adjusted Hazard ratio* (95% CI) |
P for interaction | ||
---|---|---|---|
Men (n = 37010) | Women (n = 10301) | ||
Cumulative Resting Heart Rate | |||
Change per SD | 1.35 (1.21–1.51) | 1.62 (1.08–2.44) | 0.857 |
Quartiles | 0.902 | ||
Q1:<267.90 | 1 (Reference) | 1 (Reference) | |
Q2:267.90–292.84 | 1.09 (0.87–1.37) | 0.94 (0.43–2.07) | |
Q3:292.85–322.84 | 1.10 (0.86–1.39) | 0.95 (0.41–2.19) | |
Q4:≥322.85 | 1.40 (1.07–1.84) | 1.28 (0.47–3.48) | |
P for trend | 0.037 | 0.830 | |
The number of visits with a higher RHR | 0.180 | ||
Never | 1 (Reference) | 1 (Reference) | |
At 1 study visit | 1.37 (1.16–1.62) | 1.11 (0.59–2.08) | |
At 2 study visits | 1.57 (1.25–1.97) | 2.54 (1.20–5.40) | |
At 3 study visits | 1.72 (1.22–2.49) | 3.39 (1.14–10.08) | |
P for trend | <0.001 | 0.038 |
*Adjusted for age, sex, time1–2, time2–3, mean systolic blood pressure, smoking, drinking, physical activity, body mass index, hypertension, diabetes mellitus, hyperlipidemia, stroke, cancer and baseline resting heart rate by multivariate Cox models.