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. 2017 Jan 9;7:40404. doi: 10.1038/srep40404

Figure 4. Intrahepatic mRNA levels of IP-10, IFN-γ, and IL-4 in chronic hepatitis B patients with or without fibrosis.

Figure 4

Real-time qRT-PCR was conducted to quantify the mRNA levels of intrahepatic IP-10, IFN-γ, and IL-4 in the CHB patients without or with fibrosis as described in the Materials and Methods section. The relative mRNA levels of intrahepatic IP-10, IFN-γ, and IL-4 were calculated by comparative Ct analysis after normalization for the quantity of GAPDH in the same samples and were represented as 2-△△Ct values for controls (the F0 group), which were set equal 1. ♦♦♦Differs from controls (the F0 group), P < 0.05; ★★★differs from mild or minimal fibrosis (the F1–2 group), P < 0.05; ▴▴▴differs from moderate fibrosis (the F3–4 group), P < 0.05. (a) IP-10; (b) IFN-γ; (c) IL-4.