Table 4. The relationship between pri-let-7e rs8111742, pri-miR-365b rs121224, pri-miR-4795 rs1002765 and the risk of intestinal type and diffuse type gastric cancer.
| Variables | Control group | Intestinal type gastric cancer | Diffuse type gastric cancer | Intestinal type gastric cancer vs. Control group |
Diffuse type gastric cancer vs. Control group |
||
|---|---|---|---|---|---|---|---|
| P value | OR (95%CI) | P value | OR (95%CI) | ||||
| pri-let7e rs8111742 | |||||||
| GG | 389(53.4) | 145(53.5) | 185(50.3) | 1.00 | 1.00 | ||
| GA | 285(39.1) | 107(39.5) | 146(39.7) | 0.917 | 1.02(0.75–1.38) | 0.566 | 1.08(0.83–1.42) |
| AA | 55(7.5) | 19(7.0) | 37(10.1) | 0.731 | 0.90(0.51–1.62) | 0.161 | 1.40(0.88–2.23) |
| AA + GA vs. GG | 0.985 | 1.00(0.75–1.34) | 0.325 | 1.14(0.88–1.48) | |||
| AA vs. GA + GG | 0.692 | 0.89(0.50–1.58) | 0.173 | 1.37(0.87–2.15) | |||
| pri-miR-365b rs121224 | |||||||
| CC | 138(18.9) | 59(21.8) | 58(15.8) | 1.00 | 1.00 | ||
| CG | 362(49.7) | 132(48.7) | 199(54.1) | 0.941 | 1.01(0.72–1.42) | 0.456 | 1.12(0.83–1.50) |
| GG | 229(31.4) | 80(29.5) | 111(30.2) | 0.336 | 1.23(0.81–1.86) | 0.477 | 0.87(0.59–1.29) |
| CG + GG vs. CC | 0.665 | 1.07(0.78–1.47) | 0.731 | 1.05(0.79–1.39) | |||
| GG vs. CG + CC | 0.283 | 1.22(0.85–1.74) | 0.232 | 0.81(0.57–1.14) | |||
| pri-miR4795 rs1002765 | |||||||
| GG | 262(35.9) | 101(37.3) | 142(38.6) | 1.00 | 1.00 | ||
| GA | 357(49.0) | 124(45.8) | 181(49.2) | 0.499 | 0.90(0.65–1.23) | 0.531 | 0.91(0.69–1.21) |
| AA | 110(15.1) | 46(17.0) | 45(12.2) | 0.721 | 1.08(0.70–1.68) | 0.163 | 0.74(0.49–1.13) |
| AA + GA vs. GG | 0.686 | 0.94(0.70–1.27) | 0.318 | 0.87(0.67–1.14) | |||
| AA vs. GA + GG | 0.509 | 1.14(0.77–1.70) | 0.192 | 0.77(0.53–1.14) | |||