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. 2017 Jan 9;7:40237. doi: 10.1038/srep40237

Figure 5. OA enhanced endothelium-dependent vasodilatation via PPARδ.

Figure 5

Rat aortic arteries were pre-contracted by 60 mM K+ (a) or 10 μM Phe (b) followed by the cumulative addition of vehicle control or OA. Data were shown as mean ± SEM (n = 3. *P < 0.05, ***P < 0.001 vs. vehicle control). (c) Arterial rings were incubated in medium contained 30 mM glucose in the presence of 10 μM OA for 12 h, and ACh-induced vasodilatation was tested by using Multi Myograph System. Data are shown as mean ± SEM (n = 7). *P < 0.05, ***P < 0.001 vs. vehicle control, ###P < 0.05 vs. HG. (d) Arterial rings were incubated with GSK0660 (1 μM) for 1 h followed by the cumulative addition of OA pre-contracted by Phe (n = 5). ***P < 0.001 vs. vehicle control, ##P < 0.01, ###P < 0.001 vs. OA.