Figure 7. Gomisin N (GN) prevents HFD-induced obesity and ameliorates serum biochemical parameters.

C57BL/6 mice were fed a normal diet (ND) or high-fat diet (HFD) for six weeks, and a low or high dose of GN was administered to the HFD-fed mice for an additional eight weeks. (A) Final body weight. (B) Final epididymal adipose tissue weight. (C) H&E staining (scale bar, 500 μm) (D) Serum glucose level. (E) Serum triglyceride level. (F) Serum total cholesterol level. The data are presented as the mean ± SEM for six mice. *P < 0.05, **P < 0.01 vs. ND fed mice. ^#P < 0.05 vs. HFD fed mice alone.