Table 1.
Comparison of different parameters in the investigated groups (mean ± SD, range).
Fertile men | Fertile men with Vx | OAT men | OAT men with Vx | |
---|---|---|---|---|
n | 52 | 43 | 62 | 63 |
Age (years) | 30.0 ± 2.9 (25–37) | 30.3 ± 3.8 (25–39) | 29.3 ± 3.3 (23–36) | 29.0 ± 3.6 (24–39) |
Sperm count (106/ml) | 70.2 ± 0.6 (21–97) | 68.1 ± 7.5 (31–86) | 7.9 ± 3.1 (1.6–12)a,b | 7.4 ± 2.8(2–12)a,b |
Sperm motility (%) | 60.4 ± 6.7 (45–71) | 58.8 ± 5.2 (48–65) | 21.5 ± 7.9 (9–36)a,b | 14.6 ± 6.6 (5–25)a,b |
Sperm normal morphology (%) | 6.8 ± 1.0 (6–9) | 5.93 ± 0.82 (4–7) | 2.7 ± 1 (0–4)a,b | 2.8 ± 0.5 (1–3)a,b |
Seminal BAX | 1.24 ± 0.4 (0.1–2.04) | 7.0 ± 1.5 (4–9.6)a | 9.7 ± 1 (7.7–12)a,b | 13.6 ± 2.6 (10.1–17.6)a,b,c |
Seminal BCl2 | 1.3 ± 0.4 (0.44–1.9) | 0.82 ± 0.5 (0.23–1.78)a | 0.45 ± 0.1 (0.11–0.62)a,b | 0.23 ± 0.1 (0.12–0.46)a,b,c |
Seminal GPx (U/ml) | 57.5 ± 4.5 (39–68.7) | 33.5 ± 2.5 (28.9–39.1)a | 27.9 ± 3.8 (15.4–37.4)a,b | 19.9 ± 3.9 (14.2–28.2)a,b,c |
Seminal MDA (nmol/ml) | 1.2 ± 0.4 (0.09–2.03) | 6.2 ± 1.6 (2.7–9.12)a | 7.6 ± 1.6 (5–11)a,b | 10.6 ± 1.9 (6.8–14.2)a,b,c |
Seminal miRNA-122 | 54.3 ± 4.2 (40.7–68.4) | 33.6 ± 4.5 (25.8–43.7)a | 26.8 ± 5.1 (16.9–42)a,b | 20.0 ± 4.7 (10.2–33.8)a,b,c |
Seminal miRNA-181-a | 23.1 ± 3.0 (16.4–30.6) | 14.9 ± 2.5 (9.8–20.3)a | 13.5 ± 3.2 (7.1–25.8)a,b | 7.4 ± 1.9 (4.03–10.8)a,b,c |
Seminal miRNA -34c-5 | 10.9 ± 1.8 (7.1–14.8) | 8.3 ± 1.6 (5.04–11.6)a | 6.7 ± 2.0(3.2–10.8)a,b | 2.8 ± 1 (1.7–4.8)a,b,c |
aStatistical difference compared with fertile men (controls).
bStatistical difference compared with fertile men with Vx.
cStatistical difference compared with OAT without Vx.