Figure 3.

Effect of biotin supplementation on liver morphology in mice fed a biotin-supplemented diet for 8 weeks. Paraffin sections stained by hematoxylin and eosin. (a) Control group's representative image showing a normal portal triad. (b) Supplemented group. Left panel: representative image, showing an altered triad with dilated sinusoids and increased number of bile ducts. Right panel: enlarged portal vein with adjacent portal vein branch. pv: portal vein; ha: hepatic artery; bd: bile duct; ds: dilated sinusoids; pvb: portal vein branch. Scale bar represents 100 μm.