Table 1. . Features of pharmacogenetic testing laboratories and summary of analysis of consent forms and test requisitions (n = 35).
| N | Percentage | |
|---|---|---|
|
Type of laboratory | ||
| Reference laboratories (offers multiple tests) |
20 |
57% |
| Laboratories offering PGx testing only† |
15 |
43% |
| Commercial lab |
30 |
86% |
| Academic lab |
5 |
14TT% |
|
Type of PGx test offered | ||
| Offers single-gene PGx tests only |
8 |
23% |
| Offers panel PGx tests |
17 |
49% |
| Offers both single-gene and panel |
10 |
29% |
|
Laboratories with accessible informed consent |
22 |
63% |
|
Type of consent | ||
| Patient-signed PGx-specific consent form |
3 |
14% |
| Patient-signed general genetic testing consent form |
8 |
36% |
| Patient-signed consent statement within requisition form |
4 |
18% |
| Provider assent only required |
1 |
5% |
| No consent/assent collected by lab |
6 |
27% |
|
Readability |
Average |
Range |
| Word count (overall) |
568.2 |
68–1040 |
| Word Count (patient consent embedded in test requisition) |
231.5 |
68–430 |
| Word Count (patient consent as a separate form) |
680.4 |
363–1040 |
| Flesch–Kincaid Reading Ease score (overall)‡ |
39.8 |
24–76.1 |
| Flesch–Kincaid Reading Grade (overall)§ | 12.5 | 5.6–16.9 |
†Includes laboratories offering PGx and toxicology testing, but no other gene-based tests.
‡Calculated based on average number of syllables per word and words per sentence (0–100 scale; 0 = very difficult and 100 = very easy).
§Text ranked on a US grade-school level based on the average number of syllables per word and words per sentence.
PGx: Pharmacogenetic.