Table 3. Drug-resistance profile and putative resistance determinants of N. farcinica IFM 10152.
| Drug | MIC, μg/ml | Putative resistance determinant (protein identification) |
|---|---|---|
| Ampicillin | 32 | β-lactamase (Nfa23080, Nfa 19770, and Nfa48460) |
| Aztreonam | >32 | |
| Ceftazidime | >32 | |
| Cefaclor | >32 | |
| Cefditoren | 4 | |
| Cefazolin | >32 | |
| Cefmetazone | 16 | |
| Cefotiam | 8 | |
| Ceftriaxone | 4 | |
| Cefotaxime | 4 | |
| Ceftizoxime | >32 | |
| Flomoxef | 4 | |
| Faropenem | 16 | |
| Latamoxef | >32 | |
| Meropenem | 2 | |
| Penicillin | >8 | |
| Piperacillin | >64 | |
| Imipenem | 0.25 | |
| Arbekacin | <0.25 | |
| Amikacin | <1 | |
| Gentamicin | >16 | APH(2″) (Nfa31340) |
| Kanamycin | 64 | APH(3′) (Nfa38480) |
| Streptomycin | 16 | APH(6) (Nfa38620) |
| Clarithromycin | 4 | rRNA methyltransferase (Nfa27210 and Nfa47240) |
| Erythromycin | >16 | |
| Clindamycin | 16 | |
| Ofloxacin | <0.5 | |
| Tosufloxacin | 0.25 | |
| Chloramphenicol | 64 | Efflux pump (Nfa 18410) |
| Fosfomycin | >32 | MurA (Nfa 10690) |
| Sulfamethoxazole | 19 | FoIP (Nfa4000) |
| Trimethoprim | 1 | |
| Rifampin | >16 | Monooxygenase (Nfa35380) and RpoB2 (Nfa46460) |
| Minocycline | 2 |
MIC, minimum inhibitory concentration.